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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
27.88
Human Site:
S82
Identified Species:
43.81
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S82
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
Q63
K
G
P
A
K
I
H
Q
A
L
K
E
D
I
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S113
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S82
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Rat
Rattus norvegicus
Q9JJ31
780
90872
S82
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
S81
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Chicken
Gallus gallus
XP_417163
809
94020
S111
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Frog
Xenopus laevis
Q6GPF3
768
88937
Y74
H
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S82
Q
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
G70
R
S
S
G
K
T
G
G
A
Q
L
V
G
K
K
Honey Bee
Apis mellifera
XP_623958
789
91733
A84
Q
A
Q
Q
R
V
L
A
H
Q
E
E
Q
A
L
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
K66
D
Y
V
H
E
A
N
K
R
I
R
S
L
Q
T
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
H94
Q
A
K
Q
R
V
L
H
D
Q
D
E
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
R67
Q
Q
L
Y
D
K
Y
R
E
A
F
E
E
Y
I
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
I86
T
I
L
V
G
S
E
I
Y
E
K
L
K
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
100
100
6.6
100
N.A.
6.6
66.6
0
60
P-Site Similarity:
100
40
N.A.
100
N.A.
100
100
N.A.
100
100
13.3
100
N.A.
26.6
86.6
0
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
54
0
7
0
7
14
7
0
0
0
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
0
7
0
54
47
7
0
0
% D
% Glu:
0
0
0
0
14
0
7
0
7
7
7
27
14
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
7
0
14
7
0
7
7
0
7
0
0
7
0
0
% G
% His:
7
0
7
7
0
0
7
7
54
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
0
7
0
7
0
0
0
7
7
% I
% Lys:
7
7
7
0
14
14
0
7
0
0
14
0
7
7
7
% K
% Leu:
0
0
14
0
0
0
67
0
0
7
14
7
7
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
67
7
54
14
0
0
0
7
0
67
0
0
7
7
0
% Q
% Arg:
7
0
0
0
60
0
0
7
7
0
7
7
0
0
0
% R
% Ser:
0
7
7
0
0
7
0
47
0
0
0
7
7
0
0
% S
% Thr:
7
0
0
0
0
7
0
0
7
0
0
0
47
0
7
% T
% Val:
0
0
7
7
0
60
0
0
0
0
0
7
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
7
7
7
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _